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Inhibition of selenoprotein synthesis is not the mechanism by which auranofin inhibits growth of Clostridioides difficile

Clostridioides difficile infections (CDIs) are responsible for a significant number of antibiotic-associated diarrheal cases. The standard-of-care antibiotics for C. difficile are limited to fidaxomicin and vancomycin, with the recently obsolete metronidazole recommended if both are unavailable. No...

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Detalles Bibliográficos
Autores principales: Johnstone, Michael A., Holman, Matthew A., Self, William T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484987/
https://www.ncbi.nlm.nih.gov/pubmed/37679389
http://dx.doi.org/10.1038/s41598-023-36796-9