mTORC2 regulates auditory hair cell structure and function

mTOR broadly controls cell growth, but little is known about the role of mTOR complex 2 (mTORC2) in the inner ear. To investigate the role of mTORC2 in sensory hair cells (HCs), we generated HC-specific Rictor knockout (HC-RicKO) mice. HC-RicKO mice exhibited early-onset, progressive, and profound h...

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Detalles Bibliográficos
Autores principales: Cortada, Maurizio, Levano, Soledad, Hall, Michael N., Bodmer, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484995/
https://www.ncbi.nlm.nih.gov/pubmed/37694145
http://dx.doi.org/10.1016/j.isci.2023.107687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484995/
https://www.ncbi.nlm.nih.gov/pubmed/37694145
http://dx.doi.org/10.1016/j.isci.2023.107687

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