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mTORC2 regulates auditory hair cell structure and function

mTOR broadly controls cell growth, but little is known about the role of mTOR complex 2 (mTORC2) in the inner ear. To investigate the role of mTORC2 in sensory hair cells (HCs), we generated HC-specific Rictor knockout (HC-RicKO) mice. HC-RicKO mice exhibited early-onset, progressive, and profound h...

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Detalles Bibliográficos
Autores principales:	Cortada, Maurizio, Levano, Soledad, Hall, Michael N., Bodmer, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484995/ https://www.ncbi.nlm.nih.gov/pubmed/37694145 http://dx.doi.org/10.1016/j.isci.2023.107687

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