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In vivo deuterium magnetic resonance imaging of xenografted tumors following systemic administration of deuterated water

In vivo deuterated water ((2)H(2)O) labeling leads to deuterium ((2)H) incorporation into biomolecules of proliferating cells and provides the basis for its use in cell kinetics research. We hypothesized that rapidly proliferating cancer cells would become preferentially labeled with (2)H and, there...

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Detalles Bibliográficos
Autores principales: Brender, Jeffrey R., Assmann, Julian C., Farthing, Don E., Saito, Keita, Kishimoto, Shun, Warrick, Kathrynne A., Maglakelidze, Natella, Larus, Terri L., Merkle, Hellmut, Gress, Ronald E., Krishna, Murali C., Buxbaum, Nataliya P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485001/
https://www.ncbi.nlm.nih.gov/pubmed/37679461
http://dx.doi.org/10.1038/s41598-023-41163-9