MC1R signaling through the cAMP-CREB/ATF-1 and ERK-NFκB pathways accelerates G1/S transition promoting breast cancer progression

MC1R, a G-protein coupled receptor, triggers ultraviolet light-induced melanin synthesis and DNA repair in melanocytes and is implicated in the pathogenesis of melanoma. Although widely expressed in different tissue types, its function in non-cutaneous tissue is relatively unknown. Herein, we demons...

Descripción completa

Detalles Bibliográficos
Autores principales: Chelakkot, Vipin Shankar, Thomas, Kiara, Romigh, Todd, Fong, Andrew, Li, Lin, Ronen, Shira, Chen, Shuyang, Funchain, Pauline, Ni, Ying, Arbesman, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485002/
https://www.ncbi.nlm.nih.gov/pubmed/37679505
http://dx.doi.org/10.1038/s41698-023-00437-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485002/
https://www.ncbi.nlm.nih.gov/pubmed/37679505
http://dx.doi.org/10.1038/s41698-023-00437-1

Ejemplares similares