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MC1R signaling through the cAMP-CREB/ATF-1 and ERK-NFκB pathways accelerates G1/S transition promoting breast cancer progression
MC1R, a G-protein coupled receptor, triggers ultraviolet light-induced melanin synthesis and DNA repair in melanocytes and is implicated in the pathogenesis of melanoma. Although widely expressed in different tissue types, its function in non-cutaneous tissue is relatively unknown. Herein, we demons...
Autores principales: | Chelakkot, Vipin Shankar, Thomas, Kiara, Romigh, Todd, Fong, Andrew, Li, Lin, Ronen, Shira, Chen, Shuyang, Funchain, Pauline, Ni, Ying, Arbesman, Joshua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485002/ https://www.ncbi.nlm.nih.gov/pubmed/37679505 http://dx.doi.org/10.1038/s41698-023-00437-1 |
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