Sinus venosus adaptation models prolonged cardiovascular disease and reveals insights into evolutionary transitions of the vertebrate heart

How two-chambered hearts in basal vertebrates have evolved from single-chamber hearts found in ancestral chordates remains unclear. Here, we show that the teleost sinus venosus (SV) is a chamber-like vessel comprised of an outer layer of smooth muscle cells. We find that in adult zebrafish nr2f1a mu...

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Detalles Bibliográficos
Autores principales: Gafranek, Jacob T., D’Aniello, Enrico, Ravisankar, Padmapriyadarshini, Thakkar, Kairavee, Vagnozzi, Ronald J., Lim, Hee-Woong, Salomonis, Nathan, Waxman, Joshua S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485058/
https://www.ncbi.nlm.nih.gov/pubmed/37679366
http://dx.doi.org/10.1038/s41467-023-41184-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485058/
https://www.ncbi.nlm.nih.gov/pubmed/37679366
http://dx.doi.org/10.1038/s41467-023-41184-y

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