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Sinus venosus adaptation models prolonged cardiovascular disease and reveals insights into evolutionary transitions of the vertebrate heart
How two-chambered hearts in basal vertebrates have evolved from single-chamber hearts found in ancestral chordates remains unclear. Here, we show that the teleost sinus venosus (SV) is a chamber-like vessel comprised of an outer layer of smooth muscle cells. We find that in adult zebrafish nr2f1a mu...
Autores principales: | Gafranek, Jacob T., D’Aniello, Enrico, Ravisankar, Padmapriyadarshini, Thakkar, Kairavee, Vagnozzi, Ronald J., Lim, Hee-Woong, Salomonis, Nathan, Waxman, Joshua S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485058/ https://www.ncbi.nlm.nih.gov/pubmed/37679366 http://dx.doi.org/10.1038/s41467-023-41184-y |
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