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A mosaic influenza virus-like particles vaccine provides broad humoral and cellular immune responses against influenza A viruses

The development of a universal influenza vaccine to elicit broad immune responses is essential in reducing disease burden and pandemic impact. In this study, the mosaic vaccine design strategy and genetic algorithms were utilized to optimize the seasonal influenza A virus (H1N1, H3N2) hemagglutinin...

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Detalles Bibliográficos
Autores principales: Liu, Xuejie, Zhao, Tianyi, Wang, Liangliang, Yang, Zhuolin, Luo, Chuming, Li, Minchao, Luo, Huanle, Sun, Caijun, Yan, Huacheng, Shu, Yuelong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485063/
https://www.ncbi.nlm.nih.gov/pubmed/37679361
http://dx.doi.org/10.1038/s41541-023-00728-5