Production of retroviral vectors in continuous high cell density culture

ABSTRACT: Retroviral vectors derived from murine leukemia virus (MLV) are used in somatic gene therapy applications e.g. for genetic modification of hematopoietic stem cells. Recently, we reported on the establishment of a suspension viral packaging cell line (VPC) for the production of MLV vectors....

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Detalles Bibliográficos
Autores principales: Hein, Marc D., Kazenmaier, Daniel, van Heuvel, Yasemin, Dogra, Tanya, Cattaneo, Maurizio, Kupke, Sascha Y., Stitz, Jörn, Genzel, Yvonne, Reichl, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Biotechnological Products and Process Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485120/
https://www.ncbi.nlm.nih.gov/pubmed/37542575
http://dx.doi.org/10.1007/s00253-023-12689-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485120/
https://www.ncbi.nlm.nih.gov/pubmed/37542575
http://dx.doi.org/10.1007/s00253-023-12689-9

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