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Production of retroviral vectors in continuous high cell density culture

ABSTRACT: Retroviral vectors derived from murine leukemia virus (MLV) are used in somatic gene therapy applications e.g. for genetic modification of hematopoietic stem cells. Recently, we reported on the establishment of a suspension viral packaging cell line (VPC) for the production of MLV vectors....

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Detalles Bibliográficos
Autores principales:	Hein, Marc D., Kazenmaier, Daniel, van Heuvel, Yasemin, Dogra, Tanya, Cattaneo, Maurizio, Kupke, Sascha Y., Stitz, Jörn, Genzel, Yvonne, Reichl, Udo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Biotechnological Products and Process Engineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485120/ https://www.ncbi.nlm.nih.gov/pubmed/37542575 http://dx.doi.org/10.1007/s00253-023-12689-9

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