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Supplemental fibrinogen restores thrombus formation in cardiopulmonary bypass-induced platelet dysfunction ex vivo

BACKGROUND: Major cardiac surgery related blood loss is associated with increased postoperative morbidity and mortality. Platelet dysfunction is believed to contribute to post-cardiopulmonary bypass (CPB)-induced microvascular bleeding. We hypothesised that moderately hypothermic CPB induces platele...

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Detalles Bibliográficos
Autores principales: Schoerghuber, Michael, Bärnthaler, Thomas, Prüller, Florian, Mantaj, Polina, Cvirn, Gerhard, Toller, Wolfgang, Klivinyi, Christoph, Mahla, Elisabeth, Heinemann, Akos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485366/
https://www.ncbi.nlm.nih.gov/pubmed/37087333
http://dx.doi.org/10.1016/j.bja.2023.03.010