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BRAF (V600E)/RAS Mutations and Lynch Syndrome in Patients With MSI-H/dMMR Metastatic Colorectal Cancer Treated With Immune Checkpoint Inhibitors

BACKGROUND: We pooled data from 2 cohorts of immune checkpoint inhibitors-treated microsatellite instability-high/mismatch repair-deficient (MSI/dMMR) metastatic colorectal cancer patients to evaluate the prognostic value of RAS/BRAF(V600E) mutations and Lynch syndrome (LS). PATIENTS AND METHODS: Pa...

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Detalles Bibliográficos
Autores principales: Colle, Raphael, Lonardi, Sara, Cachanado, Marine, Overman, Michael J, Elez, Elena, Fakih, Marwan, Corti, Francesca, Jayachandran, Priya, Svrcek, Magali, Dardenne, Antoine, Cervantes, Baptiste, Duval, Alex, Cohen, Romain, Pietrantonio, Filippo, André, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485382/
https://www.ncbi.nlm.nih.gov/pubmed/37023721
http://dx.doi.org/10.1093/oncolo/oyad082