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Safety and pharmacodynamics of a single infusion of danavorexton in adults with idiopathic hypersomnia

STUDY OBJECTIVES: Idiopathic hypersomnia (IH) is a chronic disorder characterized by excessive daytime sleepiness unexplained by another disorder or drug/medication use. Although the orexin system plays a role in sleep-wake regulation, orexin A levels in the cerebrospinal fluid are normal in people...

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Detalles Bibliográficos
Autores principales: Mignot, Emmanuel, Bogan, Richard K, Emsellem, Helene, Foldvary-Schaefer, Nancy, Naylor, Melissa, Neuwirth, Rachel, Faessel, Hélène, Swick, Todd, Olsson, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485568/
https://www.ncbi.nlm.nih.gov/pubmed/36883238
http://dx.doi.org/10.1093/sleep/zsad049