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Redirector of Vaccine-induced Effector Responses (RoVER) for specific killing of cellular targets

BACKGROUND: In individuals with malignancy or HIV-1 infection, antigen-specific cytotoxic T lymphocytes (CTLs) often display an exhausted phenotype with impaired capacity to eliminate the disease. Existing cell-based immunotherapy strategies are often limited by the requirement for adoptive transfer...

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Detalles Bibliográficos
Autores principales: Konrad, Christina V., Iversen, Emma F., Gunst, Jesper D., Monrad, Ida, Holleufer, Andreas, Hartmann, Rune, Østergaard, Lars J., Søgaard, Ole S., Schleimann, Mariane H., Tolstrup, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485592/
https://www.ncbi.nlm.nih.gov/pubmed/37672868
http://dx.doi.org/10.1016/j.ebiom.2023.104785