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New insights into RNA processing by the eukaryotic tRNA splicing endonuclease

Through its role in intron cleavage, tRNA splicing endonuclease (TSEN) plays a critical function in the maturation of intron-containing pre-tRNAs. The catalytic mechanism and core requirement for this process is conserved between archaea and eukaryotes, but for decades, it has been known that eukary...

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Detalles Bibliográficos
Autores principales: Hayne, Cassandra K., Sekulovski, Samoil, Hurtig, Jennifer E., Stanley, Robin E., Trowitzsch, Simon, van Hoof, Ambro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485636/
https://www.ncbi.nlm.nih.gov/pubmed/37544645
http://dx.doi.org/10.1016/j.jbc.2023.105138