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CXCR5 and TIM-3 expressions define distinct exhausted T cell subsets in experimental cutaneous infection with Leishmania mexicana

T-cell exhaustion is a key stage in chronic infections since it limits immunopathology, but also hinders the elimination of pathogens. Exhausted T (Tex) cells encompass dynamic subsets, including progenitor cells that sustain long-term immunity through their memory/stem like properties, and terminal...

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Detalles Bibliográficos
Autores principales: Diupotex, Mariana, Zamora-Chimal, Jaime, Gajón, Julián A., Bonifaz, Laura C., Becker, Ingeborg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485697/
https://www.ncbi.nlm.nih.gov/pubmed/37691941
http://dx.doi.org/10.3389/fimmu.2023.1231836