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PET Evaluation of the Novel F-18 Labeled Reversible Radioligand [(18)F]GEH200449 for Detection of Monoamine Oxidase-B in the Non-Human Primate Brain

[Image: see text] Positron emission tomography (PET) using radioligands for the enzyme monoamine oxidase B (MAO-B) is increasingly applied as a marker for astrogliosis in neurodegenerative disorders. In the present study, a novel reversible fluorine-18 labeled MAO-B compound, [(18)F]GEH200449, was e...

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Detalles Bibliográficos
Autores principales: Varnäs, Katarina, Nag, Sangram, Halldin, Christer, Farde, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485887/
https://www.ncbi.nlm.nih.gov/pubmed/37587571
http://dx.doi.org/10.1021/acschemneuro.3c00332