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PET Evaluation of the Novel F-18 Labeled Reversible Radioligand [(18)F]GEH200449 for Detection of Monoamine Oxidase-B in the Non-Human Primate Brain
[Image: see text] Positron emission tomography (PET) using radioligands for the enzyme monoamine oxidase B (MAO-B) is increasingly applied as a marker for astrogliosis in neurodegenerative disorders. In the present study, a novel reversible fluorine-18 labeled MAO-B compound, [(18)F]GEH200449, was e...
Autores principales: | Varnäs, Katarina, Nag, Sangram, Halldin, Christer, Farde, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485887/ https://www.ncbi.nlm.nih.gov/pubmed/37587571 http://dx.doi.org/10.1021/acschemneuro.3c00332 |
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