Cargando…

Mapping HDX-MS Data to Protein Conformations through Training Ensemble-Based Models

[Image: see text] An original approach that adopts machine learning inference to predict protein structural information using hydrogen–deuterium exchange mass spectrometry (HDX-MS) is described. The method exploits an in-house optimization program that increases the resolution of HDX-MS data from pe...

Descripción completa

Detalles Bibliográficos
Autores principales: Salmas, Ramin E., Harris, Matthew J., Borysik, Antoni J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485923/
https://www.ncbi.nlm.nih.gov/pubmed/37550799
http://dx.doi.org/10.1021/jasms.3c00145