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Mesenchymal stem cells in synovial fluid increase in number in response to synovitis and display more tissue-reparative phenotypes in osteoarthritis

BACKGROUND: Synovial fluid mesenchymal stem cells (SF-MSCs) originate in the synovium and contribute to the endogenous repair of damaged intra-articular tissues. Here, we clarified the relationship between their numbers and joint structural changes during osteoarthritis (OA) progression and investig...

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Detalles Bibliográficos
Autores principales: Furuoka, Hideto, Endo, Kentaro, Sekiya, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485949/
https://www.ncbi.nlm.nih.gov/pubmed/37679780
http://dx.doi.org/10.1186/s13287-023-03487-1