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The gut microbiome changes in wild type and IL-18 knockout mice after 9.0 Gy total body irradiation

BACKGROUND: Recent studies have shown that gut microbiome plays important roles in response to radiation exposure. IL-18, an inflammatory cytokine, is highly elevated in mice, mini-pigs and nonhuman primates after radiation exposure. Blocking IL-18 using its endogenous binding protein (IL-18BP) incr...

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Detalles Bibliográficos
Autores principales: Cui, Wanchang, Hull, Lisa, Zizzo, Alex, Wang, Li, Lin, Bin, Zhai, Min, Xiao, Mang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485964/
https://www.ncbi.nlm.nih.gov/pubmed/37679818
http://dx.doi.org/10.1186/s42523-023-00262-8