ESRRG-PKM2 axis reprograms metabolism to suppress esophageal squamous carcinoma progression and enhance anti-PD-1 therapy efficacy

BACKGROUND: Glycolysis under normoxic conditions, known as the Warburg effect, confers a selective advantage for the survival and proliferation of many tumors. In this study, we investigated the role of estrogen-related receptor gamma (ESRRG) in metabolic reprogramming in esophageal squamous cell ca...

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Detalles Bibliográficos
Autores principales: Wang, Tianxiao, Zhu, Yongjun, Chen, Lu, Zhang, WenXin, Qi, Huijie, Shi, Xiaojin, Zhong, Mingkang, Chen, Haifei, Li, Qunyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485992/
https://www.ncbi.nlm.nih.gov/pubmed/37679788
http://dx.doi.org/10.1186/s12967-023-04347-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485992/
https://www.ncbi.nlm.nih.gov/pubmed/37679788
http://dx.doi.org/10.1186/s12967-023-04347-5

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