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ESRRG-PKM2 axis reprograms metabolism to suppress esophageal squamous carcinoma progression and enhance anti-PD-1 therapy efficacy
BACKGROUND: Glycolysis under normoxic conditions, known as the Warburg effect, confers a selective advantage for the survival and proliferation of many tumors. In this study, we investigated the role of estrogen-related receptor gamma (ESRRG) in metabolic reprogramming in esophageal squamous cell ca...
Autores principales: | Wang, Tianxiao, Zhu, Yongjun, Chen, Lu, Zhang, WenXin, Qi, Huijie, Shi, Xiaojin, Zhong, Mingkang, Chen, Haifei, Li, Qunyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485992/ https://www.ncbi.nlm.nih.gov/pubmed/37679788 http://dx.doi.org/10.1186/s12967-023-04347-5 |
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