Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation

Among transmissible spongiform encephalopathies or prion diseases affecting humans, sporadic forms such as sporadic Creutzfeldt–Jakob disease are the vast majority. Unlike genetic or acquired forms of the disease, these idiopathic forms occur seemingly due to a random event of spontaneous misfolding...

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Detalles Bibliográficos
Autores principales: Eraña, Hasier, Díaz-Domínguez, Carlos M., Charco, Jorge M., Vidal, Enric, González-Miranda, Ezequiel, Pérez-Castro, Miguel A., Piñeiro, Patricia, López-Moreno, Rafael, Sampedro-Torres-Quevedo, Cristina, Fernández-Veiga, Leire, Tasis-Galarza, Juan, Lorenzo, Nuria L., Santini-Santiago, Aileen, Lázaro, Melisa, García-Martínez, Sandra, Gonçalves-Anjo, Nuno, San-Juan-Ansoleaga, Maitena, Galarza-Ahumada, Josu, Fernández-Muñoz, Eva, Giler, Samanta, Valle, Mikel, Telling, Glenn C., Geijó, Mariví, Requena, Jesús R., Castilla, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486007/
https://www.ncbi.nlm.nih.gov/pubmed/37679832
http://dx.doi.org/10.1186/s40478-023-01640-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486007/
https://www.ncbi.nlm.nih.gov/pubmed/37679832
http://dx.doi.org/10.1186/s40478-023-01640-8

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