Biophysical characterization of PVR family interactions and therapeutic antibody recognition to TIGIT

The clinical successes of immune checkpoint blockade have invigorated efforts to activate T cell-mediated responses against cancer. Targeting members of the PVR family, consisting of inhibitory receptors TIGIT, CD96, and CD112R, has been an active area of clinical investigation. In this study, the b...

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Detalles Bibliográficos
Autores principales: Diong, SJ J., Jashnani, Aarti, Drake, Andrew W., Bee, Christine, Findeisen, Felix, Dollinger, Gavin, Wang, Feng, Rajpal, Arvind, Strop, Pavel, Lee, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486284/
https://www.ncbi.nlm.nih.gov/pubmed/37675979
http://dx.doi.org/10.1080/19420862.2023.2253788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486284/
https://www.ncbi.nlm.nih.gov/pubmed/37675979
http://dx.doi.org/10.1080/19420862.2023.2253788

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