Amorphous Solid Forms of Ranolazine and Tryptophan and Their Relaxation to Metastable Polymorphs

[Image: see text] Different methods were explored for the amorphization of ranolazine, a sparingly soluble anti-anginal drug, such as mechanochemistry, quench-cooling, and solvent evaporation from solutions. Amorphous phases, with T(g) values lower than room temperature, were obtained by cryo-millin...

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Detalles Bibliográficos
Autores principales: Silva, Joana F. C., Pereira Silva, Pedro S., Ramos Silva, Manuela, Fantechi, Elvira, Chelazzi, Laura, Ciattini, Samuele, Eusébio, M. Ermelinda S., Rosado, Mário T. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486308/
https://www.ncbi.nlm.nih.gov/pubmed/37692331
http://dx.doi.org/10.1021/acs.cgd.3c00565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486308/
https://www.ncbi.nlm.nih.gov/pubmed/37692331
http://dx.doi.org/10.1021/acs.cgd.3c00565

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