Frequency of CDH1, CTNNA1 and CTNND1 Germline Variants in Families with Diffuse and Mixed Gastric Cancer

SIMPLE SUMMARY: Hereditary diffuse gastric cancer (HDGC) is caused by germline pathogenic variants in the CDH1 and CTNNA1 genes and is characterized by a high prevalence of diffuse gastric cancer and lobular breast cancer. We aimed to evaluate the contribution of CTNNA1 and CTNND1 germline variants...

Descripción completa

Detalles Bibliográficos
Autores principales: Guerra, Joana, Pinto, Carla, Pinto, Pedro, Pinheiro, Manuela, Santos, Catarina, Peixoto, Ana, Escudeiro, Carla, Barbosa, Ana, Porto, Miguel, Francisco, Inês, Lopes, Paula, Isidoro, Ana Raquel, Cunha, Ana Luísa, Albuquerque, Cristina, Claro, Isabel, Oliveira, Carla, Silva, João, Teixeira, Manuel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486404/
https://www.ncbi.nlm.nih.gov/pubmed/37686589
http://dx.doi.org/10.3390/cancers15174313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486404/
https://www.ncbi.nlm.nih.gov/pubmed/37686589
http://dx.doi.org/10.3390/cancers15174313

Ejemplares similares