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Frequency of CDH1, CTNNA1 and CTNND1 Germline Variants in Families with Diffuse and Mixed Gastric Cancer

SIMPLE SUMMARY: Hereditary diffuse gastric cancer (HDGC) is caused by germline pathogenic variants in the CDH1 and CTNNA1 genes and is characterized by a high prevalence of diffuse gastric cancer and lobular breast cancer. We aimed to evaluate the contribution of CTNNA1 and CTNND1 germline variants...

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Detalles Bibliográficos
Autores principales:	Guerra, Joana, Pinto, Carla, Pinto, Pedro, Pinheiro, Manuela, Santos, Catarina, Peixoto, Ana, Escudeiro, Carla, Barbosa, Ana, Porto, Miguel, Francisco, Inês, Lopes, Paula, Isidoro, Ana Raquel, Cunha, Ana Luísa, Albuquerque, Cristina, Claro, Isabel, Oliveira, Carla, Silva, João, Teixeira, Manuel R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486404/ https://www.ncbi.nlm.nih.gov/pubmed/37686589 http://dx.doi.org/10.3390/cancers15174313

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