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Autocrine Factors Produced by Mesenchymal Stem Cells in Response to Cell–Cell Contact Inhibition Have Anti-Tumor Properties

Recently, mesenchymal stem cell (MSC) therapies have been questioned as MSCs are capable of both promoting and inhibiting tumorigenesis. Both MSCs and tumor cells replicate to increase their population size; however, MSCs, but not tumor cells, stop dividing when they reach confluence due to cell–cel...

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Detalles Bibliográficos
Autores principales: Chen, Jerry P., Li, Rong, Jiang, Jean X., Chen, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486504/
https://www.ncbi.nlm.nih.gov/pubmed/37681882
http://dx.doi.org/10.3390/cells12172150