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Challenges and Prospects of Patient-Derived Xenografts for Cancer Research

SIMPLE SUMMARY: The patient-derived xenograft (PDX) model is the in vivo standard for cancer research as a preclinical platform. Besides its merits, we describe the general rationale of various PDX models and the standard procedures of orthotopic models of gastric adenocarcinoma. We also present cha...

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Detalles Bibliográficos
Autores principales: Jin, Jiankang, Yoshimura, Katsuhiro, Sewastjanow-Silva, Matheus, Song, Shumei, Ajani, Jaffer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486659/
https://www.ncbi.nlm.nih.gov/pubmed/37686627
http://dx.doi.org/10.3390/cancers15174352