Monitoring of Plasma EGFR Mutations during Osimertinib Treatment for NSCLC Patients with Acquired T790M Mutation

SIMPLE SUMMARY: The sensitive PNA-LNA clamp method could highly detect EGFR gene mutations in plasma. Plasma clearance of the activating gene mutation and the T790M mutation was observed in more than 70% of patients treated with osimertinib, and its clearance was correlated with the efficacy of osim...

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Detalles Bibliográficos
Autores principales: Watanabe, Kana, Saito, Ryota, Miyauchi, Eisaku, Nagashima, Hiromi, Nakamura, Atsushi, Sugawara, Shunichi, Tanaka, Nobuyuki, Terasaki, Hiroshi, Fukuhara, Tatsuro, Maemondo, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486675/
https://www.ncbi.nlm.nih.gov/pubmed/37686506
http://dx.doi.org/10.3390/cancers15174231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486675/
https://www.ncbi.nlm.nih.gov/pubmed/37686506
http://dx.doi.org/10.3390/cancers15174231

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