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Lysophosphatidic Acid Signalling Regulates Human Sperm Viability via the Phosphoinositide 3-Kinase/AKT Pathway

Lysophosphatidic acid (LPA) signalling is essential for maintaining germ cell viability during mouse spermatogenesis; however, its role in human spermatozoa is unknown. We previously demonstrated that peroxiredoxin 6 (PRDX6) calcium-independent phospholipase A(2) (iPLA(2)) releases lysophospholipids...

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Detalles Bibliográficos
Autores principales: Liao, Hao-Yu, O’Flaherty, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486690/
https://www.ncbi.nlm.nih.gov/pubmed/37681929
http://dx.doi.org/10.3390/cells12172196