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ACLP Activates Cancer-Associated Fibroblasts and Inhibits CD8+ T-Cell Infiltration in Oral Squamous Cell Carcinoma

SIMPLE SUMMARY: Cancer-associated fibroblasts (CAFs) are a major component of the stroma in oral squamous cell carcinoma (OSCC) and are considered important therapeutic targets. In this study, we demonstrated that aortic carboxypeptidase-like protein (ACLP) is highly expressed in CAFs of OSCC, there...

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Detalles Bibliográficos
Autores principales: Sekiguchi, Shohei, Yorozu, Akira, Okazaki, Fumika, Niinuma, Takeshi, Takasawa, Akira, Yamamoto, Eiichiro, Kitajima, Hiroshi, Kubo, Toshiyuki, Hatanaka, Yui, Nishiyama, Koyo, Ogi, Kazuhiro, Dehari, Hironari, Kondo, Atsushi, Kurose, Makoto, Obata, Kazufumi, Kakiuchi, Akito, Kai, Masahiro, Hirohashi, Yoshihiko, Torigoe, Toshihiko, Kojima, Takashi, Osanai, Makoto, Takano, Kenichi, Miyazaki, Akihiro, Suzuki, Hiromu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486706/
https://www.ncbi.nlm.nih.gov/pubmed/37686580
http://dx.doi.org/10.3390/cancers15174303