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Combination of Genomic Landsscape and 3D Culture Functional Assays Bridges Sarcoma Phenotype to Target and Immunotherapy

Genomic-based precision medicine has not only improved tumour therapy but has also shown its weaknesses. Genomic profiling and mutation analysis have identified alterations that play a major role in sarcoma pathogenesis and evolution. However, they have not been sufficient in predicting tumour vulne...

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Detalles Bibliográficos
Autores principales: de Nigris, Filomena, Meo, Concetta, Palinski, Wulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486752/
https://www.ncbi.nlm.nih.gov/pubmed/37681936
http://dx.doi.org/10.3390/cells12172204