Vascular Immune Evasion of Mesenchymal Glioblastoma Is Mediated by Interaction and Regulation of VE-Cadherin on PD-L1

SIMPLE SUMMARY: Our study identified the primary expression of PD-L1 in vascular endothelial cells that correlated with the expression of the mesenchymal markers YKL-40 and Vim and poor patient survival. YKL-40 induced VE-cad expression, which interacted with and upregulated PD-L1, leading to vascul...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Jing, Wang, Ziyi, Zhang, Xuemei, Yu, Haihui, Chen, Hui, Song, Kun, Zhang, Yang, Schwartz, Lawrence M., Chen, Hongzhuan, Liu, Yingbin, Shao, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486786/
https://www.ncbi.nlm.nih.gov/pubmed/37686533
http://dx.doi.org/10.3390/cancers15174257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486786/
https://www.ncbi.nlm.nih.gov/pubmed/37686533
http://dx.doi.org/10.3390/cancers15174257

Ejemplares similares