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Vascular Immune Evasion of Mesenchymal Glioblastoma Is Mediated by Interaction and Regulation of VE-Cadherin on PD-L1

SIMPLE SUMMARY: Our study identified the primary expression of PD-L1 in vascular endothelial cells that correlated with the expression of the mesenchymal markers YKL-40 and Vim and poor patient survival. YKL-40 induced VE-cad expression, which interacted with and upregulated PD-L1, leading to vascul...

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Detalles Bibliográficos
Autores principales:	Luo, Jing, Wang, Ziyi, Zhang, Xuemei, Yu, Haihui, Chen, Hui, Song, Kun, Zhang, Yang, Schwartz, Lawrence M., Chen, Hongzhuan, Liu, Yingbin, Shao, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486786/ https://www.ncbi.nlm.nih.gov/pubmed/37686533 http://dx.doi.org/10.3390/cancers15174257

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