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Human Mast Cells Upregulate Cathepsin B, a Novel Marker of Itch in Psoriasis

Mast cells (MCs) contribute to skin inflammation. In psoriasis, the activation of cutaneous neuroimmune networks commonly leads to itch. To dissect the unique contribution of MCs to the cutaneous neuroinflammatory response in psoriasis, we examined their density, distribution, relation to nerve fibr...

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Detalles Bibliográficos
Autores principales: West, Peter W., Tontini, Chiara, Atmoko, Haris, Kiss, Orsolya, Garner, Terence, Bahri, Rajia, Warren, Richard B., Griffiths, Christopher E. M., Stevens, Adam, Bulfone-Paus, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10486964/
https://www.ncbi.nlm.nih.gov/pubmed/37681909
http://dx.doi.org/10.3390/cells12172177