Novel Function of Cancer Stem Cell Marker ALDH1A3 in Glioblastoma: Pro-Angiogenesis through Paracrine PAI-1 and IL-8

SIMPLE SUMMARY: Hyper-angiogenesis is a characteristic of glioblastoma (GBM), and anti-angio-genesis is a crucial strategy to interfere with tumor progression in GBM therapy. We previously found a high expression of ALDH1A3 in proliferating vasculature in GBM patients, which was associated with poor...

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Detalles Bibliográficos
Autores principales: Chen, Zhen, Will, Rainer, Kim, Su Na, Busch, Maike Anna, Dünker, Nicole, Dammann, Philipp, Sure, Ulrich, Zhu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487054/
https://www.ncbi.nlm.nih.gov/pubmed/37686698
http://dx.doi.org/10.3390/cancers15174422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487054/
https://www.ncbi.nlm.nih.gov/pubmed/37686698
http://dx.doi.org/10.3390/cancers15174422

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