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Nanoparticle Delivery of Immunostimulatory Alu RNA for Cancer Immunotherapy

It was recently found that patients with relapsing remitting multiple sclerosis exhibit widespread loss of adenosine-to-inosine (A-to-I) RNA editing, which contributes to the accumulation of immunostimulatory double-stranded Alu RNA in circulating leukocytes and an attendant increase in levels of pr...

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Detalles Bibliográficos
Autores principales: Garland, Kyle M., Kwiatkowski, Alexander J., Tossberg, John T., Crooke, Philip S., Aune, Thomas M., Wilson, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487107/
https://www.ncbi.nlm.nih.gov/pubmed/37691856
http://dx.doi.org/10.1158/2767-9764.CRC-22-0354