The Correlation of In Vivo MR Spectroscopy and Ex Vivo 2-Hydroxyglutarate Concentration for the Prediction of Isocitrate Dehydrogenase Mutation Status in Diffuse Glioma

Isocitrate dehydrogenase (IDH) mutation status is an important biomarker in the glioma-defining subtype and corresponding prognosis. This study proposes a straightforward method for 2-hydroxyglutarate (2-HG) quantification by MR spectroscopy for IDH mutation status detection and directly compares in...

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Detalles Bibliográficos
Autores principales: van Dijken, Bart R. J., Jeltema, Hanne-Rinck, Kłos, Justyna, van Laar, Peter Jan, Enting, Roelien H., Maatman, Ronald G. H. J., Bijsterveld, Klaas, Den Dunnen, Wilfred F. A., Dierckx, Rudi A., Sijens, Paul E., van der Hoorn, Anouk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487112/
https://www.ncbi.nlm.nih.gov/pubmed/37685329
http://dx.doi.org/10.3390/diagnostics13172791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487112/
https://www.ncbi.nlm.nih.gov/pubmed/37685329
http://dx.doi.org/10.3390/diagnostics13172791

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