Increased Osteoclastogenesis in Absence of TG2 Is Reversed by Transglutaminase Inhibition—Evidence for the Role for TG1 in Osteoclast Formation

Osteoclasts are multinucleated, bone-resorbing giant cells derived from monocyte–macrophage cell lines. Increased bone resorption results in loss of bone mass and osteoporosis. Osteoclast and bone marrow macrophages have been shown to express three TG enzymes (TG2, Factor XIII-A, and TG1) and TG act...

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Detalles Bibliográficos
Autores principales: Ebrahimi Samani, Sahar, Kaartinen, Mari T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487146/
https://www.ncbi.nlm.nih.gov/pubmed/37681871
http://dx.doi.org/10.3390/cells12172139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487146/
https://www.ncbi.nlm.nih.gov/pubmed/37681871
http://dx.doi.org/10.3390/cells12172139

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