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Development and characterization of a recombinant silk network for 3D culture of immortalized and fresh tumor‐derived breast cancer cells

Traditional cancer models rely on 2D cell cultures or 3D spheroids, which fail to recapitulate cell‐extracellular matrix (ECM) interactions, a key element of tumor development. Existing hydrogel‐based 3D alternatives lack mechanical support for cell growth and often suffer from low reproducibility....

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Detalles Bibliográficos
Autores principales: Collodet, Caterina, Blust, Kelly, Gkouma, Savvini, Ståhl, Emmy, Chen, Xinsong, Hartman, Johan, Hedhammar, My
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487315/
https://www.ncbi.nlm.nih.gov/pubmed/37693069
http://dx.doi.org/10.1002/btm2.10537