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Dual gene‐activated dermal scaffolds regulate angiogenesis and wound healing by mediating the coexpression of VEGF and angiopoietin‐1

The vascularization of dermal substitutes is a key challenge in efforts to heal deep skin defects. In this study, dual gene‐activated dermal scaffolds (DGADSs‐1) were fabricated by loading nanocomposite particles of polyethylenimine (PEI)/multiple plasmid DNAs (pDNAs) encoding vascular endothelial g...

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Detalles Bibliográficos
Autores principales: Weng, Tingting, Yang, Min, Zhang, Wei, Jin, Ronghua, Xia, Sizhan, Zhang, Manjia, Wu, Pan, He, Xiaojie, Han, Chunmao, Zhao, Xiong, Wang, Xingang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487340/
https://www.ncbi.nlm.nih.gov/pubmed/37693053
http://dx.doi.org/10.1002/btm2.10562