Protamine dose to neutralize heparin at the completion of cardiopulmonary bypass can be reduced significantly without affecting post-operative bleeding

Background: Systemic anticoagulation with heparin during cardiopulmonary bypass (CPB) should be neutralized by protamine administration to restore normal hemostasis. Our previous study showed the protamine-to-heparin ratio (P-to-H) of 1:1 (1 mg protamine:100 IU circulating heparin; 1.0 Ratio) is lik...

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Detalles Bibliográficos
Autores principales: Lee, Min-Ho, Beck, Matthew, Shann, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487347/
https://www.ncbi.nlm.nih.gov/pubmed/37682208
http://dx.doi.org/10.1051/ject/2023026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487347/
https://www.ncbi.nlm.nih.gov/pubmed/37682208
http://dx.doi.org/10.1051/ject/2023026

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