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The Dipeptide Gly-Pro (GP), Derived from Hibiscus sabdariffa, Exhibits Potent Antifibrotic Effects by Regulating the TGF-β1-ATF4-Serine/Glycine Biosynthesis Pathway

TGF-β1, a key fibrotic cytokine, enhances both the expression and translocation of the activating transcriptional factor 4 (ATF4) and activates the serine/glycine biosynthesis pathway, which is crucial for augmenting collagen production. Targeting the TGF-β1-ATF4-serine/glycine biosynthesis pathway...

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Detalles Bibliográficos
Autores principales:	Kim, HaiVin, Jang, YoungSu, Ryu, JaeSang, Seo, DaHye, Lee, Sak, Choi, SungSoo, Kim, DongHyun, Moh, SangHyun, Shin, JungU
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487435/ https://www.ncbi.nlm.nih.gov/pubmed/37686422 http://dx.doi.org/10.3390/ijms241713616

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