Brain-Derived 11S Regulator (PA28αβ) Promotes Proteasomal Hydrolysis of Elongated Oligoglutamine-Containing Peptides

Proteins with extended polyglutamine regions are associated with several neurodegenerative disorders, including Huntington’s disease. Intracellular proteolytic processing of these proteins is not well understood. In particular, it is unclear whether long polyglutamine fragments resulting from the pr...

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Detalles Bibliográficos
Autores principales: Kriachkov, Viacheslav A., Gotmanova, Natalia N., Tashlitsky, Vadim N., Bacheva, Anna V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487437/
https://www.ncbi.nlm.nih.gov/pubmed/37686081
http://dx.doi.org/10.3390/ijms241713275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487437/
https://www.ncbi.nlm.nih.gov/pubmed/37686081
http://dx.doi.org/10.3390/ijms241713275

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