CAR-NK Cells Generated with mRNA-LNPs Kill Tumor Target Cells In Vitro and In Vivo

Natural killer (NK) cells are cytotoxic lymphocytes that are critical for the innate immune system. Engineering NK cells with chimeric antigen receptors (CARs) allows CAR-NK cells to target tumor antigens more effectively. In this report, we present novel CAR mRNA-LNP (lipid nanoparticle) technology...

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Detalles Bibliográficos
Autores principales: Golubovskaya, Vita, Sienkiewicz, John, Sun, Jinying, Zhang, Shiming, Huang, Yanwei, Zhou, Hua, Harto, Hizkia, Xu, Shirley, Berahovich, Robert, Wu, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487516/
https://www.ncbi.nlm.nih.gov/pubmed/37686170
http://dx.doi.org/10.3390/ijms241713364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487516/
https://www.ncbi.nlm.nih.gov/pubmed/37686170
http://dx.doi.org/10.3390/ijms241713364

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