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Tetrahydrobiopterin as a Trigger for Vitiligo: Phototransformation during UV Irradiation

Vitiligo is a type of hypomelanosis. Tetrahydrobiopterin (H(4)Bip), the coenzyme of the initial stage of melanogenesis, appears to be a trigger for vitiligo. H(4)Bip is present in vitiligo in 3–5-fold excess and causes oxidative stress by triggering an autocatalytic cycle of excess hydrogen peroxide...

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Detalles Bibliográficos
Autores principales: Telegina, Taisiya A., Vechtomova, Yuliya L., Borzova, Vera A., Buglak, Andrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487557/
https://www.ncbi.nlm.nih.gov/pubmed/37686391
http://dx.doi.org/10.3390/ijms241713586