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Tetrahydrobiopterin as a Trigger for Vitiligo: Phototransformation during UV Irradiation
Vitiligo is a type of hypomelanosis. Tetrahydrobiopterin (H(4)Bip), the coenzyme of the initial stage of melanogenesis, appears to be a trigger for vitiligo. H(4)Bip is present in vitiligo in 3–5-fold excess and causes oxidative stress by triggering an autocatalytic cycle of excess hydrogen peroxide...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10487557/ https://www.ncbi.nlm.nih.gov/pubmed/37686391 http://dx.doi.org/10.3390/ijms241713586 |